IṢẸ́ ỌNÀ
ẸWÀ ÀTI ÌLERA
IṢẸ́ ỌWỌ́
ÀṢÀ ÀTI ÌTÀN
ÌṢERÉ
ÀYÍKÁ
OÚNJẸ ÀTI OHUN MÍMU
REVERSE ENGINEERING
SÁYẸ́ǸSÌ
ERÉ ÌDÁRAYÁ
ÌMỌ̀-Ẹ̀RỌ
ÀWỌN OHUN WÍWỌ̀
Acetoacetanilide: Aniline in Ether with Diketene Added Slowly (Gleason, Standard Oil Development, US 2,174,239)
Diketene and aniline join into acetoacetanilide, the coupling component of Hansa yellow, but neat they react so violently that the product is poor. Gleason tamed the reaction by diluting both in ether and adding the diketene slowly; the anilide simply crystallises out.
Result: crystals of acetoacetanilide.
Source: Gleason, US 2,174,239 (Standard Oil Development, 1939). Not given: yield. Picture drawn by Youblob.
Àárín
1 day
Ìlànà
1
1
Dissolve the aniline
Dissolve the aniline
Dissolve 1 part by weight of aniline in about 5 parts of ether at room temperature.
Àwọn ohun èlò fún ìgbésẹ̀ yìí:
Aniline1 part by weightÀwọn irinṣẹ́ tí a nílò:
Diethyl ether
Ìgò abẹ́-róbótó
Òǹwọ̀n ìdọ́gba2
2
Add diketene slowly
Add diketene slowly
Add 1 part of diketene slowly with stirring. Keep it at room temperature or a little above, never even locally above 80-100 C; cool if needed.
Àwọn ohun èlò fún ìgbésẹ̀ yìí:
Kétínì méjì-papọ̀1 part by weightÀwọn irinṣẹ́ tí a nílò:
Fọ́nẹ́ẹ̀lì Ìyàpa
Ẹ̀rọ Ìwọ̀n Ooru3
3
Let it crystallise
Let it crystallise
When the reaction is over, let the liquid stand; acetoacetanilide crystallises.
Àwọn irinṣẹ́ tí a nílò:
Ìgò abẹ́-róbótó4
4
Collect and wash
Collect and wash
Decant or filter off the crystals and wash them with a little cold ether.
Àwọn irinṣẹ́ tí a nílò:
Funnel Büchner (porcelain)
Bébà Ìsẹ́Diethyl etherÀwọn irinṣẹ́ tó nílò
7- Àyè
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